5-Amino-2,2-difluoro-1,3-benzodioxole is used as a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
5-Amino-2,2-difluoro-1,3-benzodioxole is used as a pharmaceutical intermediate.
Solubility
Not miscible or difficult to mix in water.
Notes
Light sensitive. Store in a cool, dry place in tightly closed container. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Mudumala Veeranarayana Reddy; Someshwar D. Dindulkar; Yeon Tae Jeong. BF3·SiO2-catalyzed one-pot synthesis of α-aminophosphonates in ionic liquid and neat conditions. Tetrahedron Letters. 2011, 52 (37), 4764-4767.
- L. W. Lawrence Woo; Paul M. Wood; Christian Bubert; Mark P. Thomas; Atul Purohit and Barry V. L. Potter. Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate. ChemMedChem. 2013, 8 (5), 779-799.