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Proteintech
C1QBP Polyclonal Antibody, CoraLite® Plus 647
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Product Details
CL647-24474
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion Protein
Conjugate
Excitation/Emission Max
654/674 nm
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MLPLLRCVPR VLGSSVAGLR AAAPASPFRQ LLQPAPRLCT RPFGLLSVRA GSERRPGLLR PRGPCACGCG CGSLHTDGDK AFVDFLSDEI KEERKIQKHK TLPKMSGGWE LELNGTEAKL VRKVAGEKIT VTFNINNSIP PTFDGEEEPS QGQKVEEQEP ELTSTPNFVV EVIKNDDGKK ALVLDCHYPE DEVGQEDEAE SDIFSIREVS FQSTGESEWK DTNYTLNTDS LDWALYDHLM DFLADRGVDN TFADELVELS TALEHQEYIT FLEDLKSFVK SQ
Target Information
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qBP; Complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; GC1q-R protein; Glycoprotein gC1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; p33; RPA; SF2AP32; splicing factor SF2-associated protein; unnamed protein product
Gene Aliases: AA407365; AA986492; C1QBP; COXPD33; D11Wsu182e; gC1Q-R; GC1QBP; gC1qR; HABP1; P32; SF2AP32; SF2P32
UniProt ID: (Human) Q07021, (Rat) O35796
Entrez Gene ID: (Human) 708, (Rat) 29681, (Mouse) 12261
complement component C1q binding
transcription corepressor activity
mRNA binding
enzyme inhibitor activity
protein kinase C binding
protein binding
hyaluronic acid binding
transcription factor binding
kininogen binding
adrenergic receptor binding
deoxyribonuclease inhibitor activity
C5-methylcytidine-containing RNA reader activity
mitochondrial ribosome binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
mRNA processing
apoptotic process
immune response
complement activation, classical pathway
RNA splicing
phosphatidylinositol 3-kinase signaling
regulation of complement activation
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of MDA-5 signaling pathway
negative regulation of RIG-I signaling pathway
mature ribosome assembly
positive regulation of apoptotic process
innate immune response
positive regulation of cell adhesion
negative regulation of mRNA splicing, via spliceosome
negative regulation of defense response to virus
positive regulation of protein kinase B signaling
positive regulation of mitochondrial translation
positive regulation of neutrophil chemotaxis
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of trophoblast cell migration
positive regulation of dendritic cell chemotaxis
immune system process
regulation of transcription, DNA-templated
ribosome biogenesis
double-strand break repair via homologous recombination
mitochondrial RNA catabolic process
adaptive immune response
cellular response to DNA damage stimulus
protein kinase B signaling
negative regulation of double-strand break repair via homologous recombination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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