Search

  • Order Status
  • Quick Order
  • Promos
Element SearchElement SearchStructure SearchStructure Search
5-(Trifluoromethyl)indole, 98%
5-(Trifluoromethyl)indole, 98%
5-(Trifluoromethyl)indole, 98%
Thermo Scientific Chemicals

5-(Trifluoromethyl)indole, 98%

CAS: 100846-24-0 | C9H6F3N | 185.149 g/mol
Have Questions?
Change viewbuttonViewtableView
Quantity:
100 mg
500 mg
ChemDexTry the chem dexTM web app
Catalog number H28782.ME
also known as H28782-ME
Price (EUR)
326,00
Each
Quantity:
500 mg
Request bulk or custom format
Price (EUR)
326,00
Each
Chemical Identifiers
CAS100846-24-0
IUPAC Name5-(trifluoromethyl)-1H-indole
Molecular FormulaC9H6F3N
InChI KeyLCFDJWUYKUPBJM-UHFFFAOYSA-N
SMILESFC(F)(F)C1=CC=C2NC=CC2=C1
View more
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Pale yellow to brown
Assay (GC)≥97.5%
Melting Point (clear melt)66.0-72.0?C
FormPowder

In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of 5-(trifluoromethyl)indole(1k) or 6-(trifluoromethyl)indole (1l) with 2a afforded the desired products 3k (86%)and 3l (86%).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
In 3-Naphthylindole construction by rhodium (II)-catalyzed regioselective direct arylation of indoles with 1-diazonaphthalen-2-(1H)-ones treatment of 5-(trifluoromethyl)indole(1k) or 6-(trifluoromethyl)indole (1l) with 2a afforded the desired products 3k (86%)and 3l (86%).

Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, light.
RUO – Research Use Only

General References:

  1. Ek Raj Baral,; Yong Rok Lee1,; Sung Hong Kim2. 3-Naphthylindole Construction by Rhodium(II)-Catalyzed Regioselective Direct Arylation of Indoles with 1-Diazonaphthalen-2-(1H)-ones. Advanced Synthesis & Catalysis. 2015, 357 (13),2883-2892.
  2. Larisa V. Politanskaya,; Igor P. Chuikov,; Vitalij D. Shteingarts. Synthesis of indoles with a polyfluorinated benzene ring . Tetrahedron. 2013 , 69 (39),8477-8486.