Kaempferol, 98+%, Thermo Scientific Chemicals
Kaempferol, 98+%, Thermo Scientific Chemicals
Kaempferol, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Kaempferol, 98+%, Thermo Scientific Chemicals

Have Questions?
Catalog NumberQuantity
J60373.MF
also known as J60373-MF
50 mg
Catalog number J60373.MF
also known as J60373-MF
Price (EUR)
153,65
Online Exclusive
170,00
Save 16,35 (10%)
Each
Quantity:
50 mg
Request bulk or custom format
Price (EUR)
153,65
Online Exclusive
170,00
Save 16,35 (10%)
Each
Chemical Identifiers
CAS520-18-3
SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)> 98.0%
Proton NMRConsistent with Structure
FormSolid
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Kaempferol, is used as an inhibitor of Fatty Acid Synthase, Cox-1 activity, and Topo I. It also Induces caspase-9-mediated apoptosis in a variety of cancer cell lines via downregulation of polo-like kinase 1 (PLK1) expression. Exhibits antioxidant activity and attenuates osteoclastic bone reabsorption in vitro. Also blocks EGF-induced histone H3Ser10 phosphorylation in mouse epidermal JB6 C141 cells.

Solubility
Soluble in DMSO or ethanol to 100mM

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Keep away fom strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Montero et al. Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids. Biochem.J. 2004, 384,( Pt 1), 19-24.
  2. Kang et al. () Downregulation of PLK-1 expression in kaempferol-induced apoptosis of MCF-7 cells. Eur.J.Pharmacol. 2009, 611 ,( 1-3), 17-21.