Nicergoline

Name: Nicergoline
SKU: J63295.03
Price: 303.00 EUR

CAS: 27848-84-6 | C24H26BrN3O3 | 484.394 g/mol

Change view

Quantity:

100 mg

1 g

Try the chem dex^TM web app

This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.

Catalog number J63295.03

also known as J63295-03

Price (EUR)

303,00

Each

Quantity:

1 g

Request bulk or custom format

Price (EUR)

303,00

Each

Chemical Identifiers

CAS27848-84-6

IUPAC Name(2S,4R,7R)-4-[(5-bromopyridine-3-carbonyloxy)methyl]-2-methoxy-6,11-dimethyl-6,11-diazatetracyclo[7.6.1.0²,⁷.0¹²,¹⁶]hexadeca-1(16),9,12,14-tetraen-6-ium

Molecular FormulaC24H27BrN3O3

InChI KeyYSEXMKHXIOCEJA-FVFQAYNVSA-O

SMILESCO[C@]12C[C@@H](COC(=O)C3=CN=CC(Br)=C3)C[NH+](C)[C@@H]1CC1=CN(C)C3=CC=CC2=C13

Specifications

Specification Sheet

Appearance (Color)White to yellow

Assay from Supplier's CofA≥97.0%

FormPowder or granular powder

Nicergoline is an ergot derivative and vasodilator which increases blood flow in the brain. Nicergoline inhibits the vasoconstrictor effect of catecholamines by inhibiting the postsynaptic α1-adrenoceptors on vascular smooth muscle.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in alcohol, chloroform, and acetone. Insoluble in water.

Notes
Protect from heat. Store away from oxidizing agents.

RUO – Research Use Only

General References:

Arcamone, F.; Glasser, A.G.; Grafnetterov, J.; Minghetti, A.; Nicolella, V. TStudies on the metabolism of ergoline derivatives: Metabolism of nicergoline∗ in man and in animals.BBiochemical Pharmacology.1972, 21, (16), 2205-2213.
Bengt Winblad.; Mario Fioravanti.; Tomas Dolezal.; Inara Logina.; Ivan Gospodinov Milanov.; Dinu Cristian Popescu.; Alina Solomon. Therapeutic Use of Nicergoline.Clinical Drug Investigation.2008, 28, (9), 533-552.