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Bexarotene, 98%, Thermo Scientific Chemicals
Catalog number: J63701.MC
100 mg, Each
Thermo Scientific Chemicals
Bexarotene, 98%, Thermo Scientific Chemicals
Catalog number: J63701.MC
100 mg, Each
Quantity
Catalog number: J63701.MC
also known as J63701-MC
Price (EUR)
Price: 130,00
Your price:
Quantity
-
Chemical Identifiers
CAS
153559-49-0
Specifications
Specification SheetForm
Powder or crystals or crystalline powder
Proton NMR
Conforms
Assay from Suppliers CofA
≥97.5%
Appearance (Color)
White to pale yellow
Description
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer's model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.
Solubility
Soluble in DMSO and ethanol
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
Bexarotene is used as a Synthetic retinoid analog with specific affinity for the retinoid X receptor, an antineoplastic agent, already approved as an oral antineoplastic agent for cutaneous T cell lymphoma and being investigated against other cancers. A study has found that bexarotene in a mouse Alzheimer′s model lowered the most toxic form of β-amyloid peptide and increased cognitive ability.
Solubility
Soluble in DMSO and ethanol
Notes
Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P312 - Call a POISON CENTER or doctor if you feel unwell
P332 + P313 - If skin irritation occurs: Get medical advice/attention
P337 + P313 - If eye irritation persists: Get medical advice/attention