Doxycycline monohydrate
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Doxycycline monohydrate
Doxycycline monohydrate
Doxycycline monohydrate
Thermo Scientific Chemicals

Doxycycline monohydrate

Doxycycline monohydrate, CAS # 17086-28-1, is the hydrated form of the tetracycline class antibiotic doxycycline. | CAS: 17086-28-1 | C22H26N2O9 | 462.455 g/mol
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25 g
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Catalog number J63805.14
also known as J63805-14
Price (EUR)
309,00
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Quantity:
25 g
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Price (EUR)
309,00
Each
Add to cart
Chemical Identifiers
CAS17086-28-1
IUPAC Name(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione hydrate
Molecular FormulaC22H26N2O9
InChI KeyADAURKPGCFUREH-UQVCFKGQSA-N
SMILESO.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=O)C(=C(/N)O)C(=O)[C@@]3(O)C(=O)C2=C(O)C2=C(O)C=CC=C12
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SpecificationsSpecification SheetSpecification Sheet
Assay (HPLC)≥ 97.0%
Appearance (Color)Yellow powder
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

General Description

  • Doxycycline monohydrate is a semi-synthetic tetracycline antibiotic with broad-spectrum activity
  • It is a tetracycline with the 5beta-hydrogen group replaced by a hydroxy group
  • Doxycycline monohydrate acts by binding the 30S ribosomal subunit and preventing polypeptide formation
  • Doxycycline monohydrate may also act on the 50S ribosomal subunit, is a known inhibitor of collagenases, and has anti-inflammatory properties

Application

  • Doxycycline can be used for study of cancers, infections, and antibiotic resistance in laboratory settings
  • Doxycycline can be used experimentally to control TET genes and induce expression of genes of interest in vitro
RUO – Research Use Only

General References:

  1. Clemens DL, Duryee MJ, Sarmiento C, Chiou A, McGowan JD, Hunter CD, Schlichte SL, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Zimmerman MC, Anderson DR. Novel Antioxidant Properties of Doxycycline. Int J Mol Sci. 2018 Dec 17;19(12):4078. doi: 10.3390/ijms19124078. PMID: 30562944; PMCID: PMC6321135.
  2. Clemens DL, Duryee MJ, Sarmiento C, Chiou A, McGowan JD, Hunter CD, Schlichte SL, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Zimmerman MC, Anderson DR. Novel Antioxidant Properties of Doxycycline. Int J Mol Sci. 2018 Dec 17;19(12):4078. doi: 10.3390/ijms19124078. PMID: 30562944; PMCID: PMC6321135.