Guanidine hydrochloride, ultrapure, 99%
Guanidine hydrochloride, ultrapure, 99%
Guanidine hydrochloride, ultrapure, 99%
Guanidine hydrochloride, ultrapure, 99%
Thermo Scientific Chemicals

Guanidine hydrochloride, ultrapure, 99%

CAS: 50-01-1 | CH6ClN3 | 95.53 g/mol
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500 g
1 kg
Catalog number J65485.22
also known as J65485-22
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100 g
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Chemical Identifiers
CAS50-01-1
IUPAC Namehydrogen guanidine chloride
Molecular FormulaCH6ClN3
InChI KeyPJJJBBJSCAKJQF-UHFFFAOYSA-N
SMILES[H+].[Cl-].NC(N)=N
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SpecificationsSpecification SheetSpecification Sheet
Solution TestSoluble in water at 6M concentration
Assay (special)≥99.0%
Appearance (Color)White
Assay (special)Nitrate: ≤0.01%
Assay (special)Sulfate: ≤0.01%
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Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized to synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized to synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

Solubility
Soluble in water and ethanol.

Notes
Hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.May agglomerate upon storage.
RUO – Research Use Only

General References:

  1. Liu, B.; Liu, M.; Liang, L.; Sun, J. Guanidine Hydrochloride/ZnI2 as Heterogeneous Catalyst for Conversion of CO2 and Epoxides to Cyclic Carbonates under Mild Conditions. Catalysts 2015, 5 (1), 119-130.
  2. Mikhail M. T.; Akentiev, A. V.; Noskov, B. A. Influence of guanidine hydrochloride and urea on the dynamic surface properties of lysozyme solutions. Mendeleev Commun 2015, 25 (4), 288-289.