Acridine Orange

Name: Acridine Orange
SKU: L13159.14
Price: 48.90 EUR

CAS: 10127-02-3 | C17H20Cl3N3Zn | 438.10 g/mol

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Catalog number L13159.14

also known as L13159-14

Price (EUR)

48,90

Each

Quantity:

25 g

Request bulk or custom format

Price (EUR)

48,90

Each

Chemical Identifiers

CAS10127-02-3

IUPAC Namezinc(2+) hydrogen N3,N3,N6,N6-tetramethylacridine-3,6-diamine trichloride

Molecular FormulaC17H20Cl3N3Zn

InChI KeyVADJQOXWNSPOQA-UHFFFAOYSA-L

SMILES[H+].[Cl-].[Cl-].[Cl-].[Zn++].CN(C)C1=CC2=NC3=CC(=CC=C3C=C2C=C1)N(C)C

Specifications

Specification Sheet

CommentSpecification differs for U.S. and non-U.S. material where indicated

Loss on Drying≤10.0% (105°C, 1 hr (U.S. specification)

Loss on Drying≤10.0% (200°C/constant wt. (non-U.S. specification)

lambda-max (UV-Vis)490-495nm (in water) (non-U.S. specification)

Specific Absorbance (E 1%/1cm)Lambda max >800 (in water) (non-U.S. specification)

Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Fluorescent stain for nucleic acids. An RNA polymerase inhibitorAcridine Orange acts as a lysosomal dye. It is used for cell-cycle studies. It plays an important role as a nucleic acid-selective fluorescent cationic dye, which is useful for cell cycle determination. Further, it serves as an inhibitor of RNA polymerase.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Biological stain.
Selvaggi, R.; Tarpani, L.; Santuari, A.; Giovagnoli, S.; Latterini, L. Silica nanoparticles assisted photodegradation of acridine orange in aqueous suspensions. Appl. Catal., B 2015, 168-169, 363-369.
Zhang, Y.; Pan, J.; Zhang, G.; Zhou, X. Intercalation of herbicide propyzamide into DNA using acridine orange as a fluorescence probe. Sens. Actuators, B 2015, 206, 630-639.