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Thermo Scientific Chemicals
(R)-(-)-Tetrahydrofurfurylamine, 98+%
CAS: 7202-43-9 | C5H11NO | 101.149 g/mol
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Catalog number L14410.03
also known as L14410-03
Price (EUR)
99,30
Each
Quantity:
1 g
Price (EUR)
99,30
Each
Chemical Identifiers
CAS7202-43-9
IUPAC Name1-(oxolan-2-yl)methanamine
Molecular FormulaC5H11NO
InChI KeyYNOGYQAEJGADFJ-UHFFFAOYNA-N
SMILESNCC1CCCO1
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Specifications
Specification Sheet
Specification SheetFormLiquid
Refractive Index1.4520-1.4560 @ 20?C
Assay (GC)≥98.0%
Appearance (Color)Clear colorless to yellow
Optical Rotation-12.9 ± 0.1? ( C = 2 in Chloroform )
(R)-(-)-Tetrahydrofurfurylamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
(R)-(-)-Tetrahydrofurfurylamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
Solubility
Fully miscible with water.
Notes
Hygroscopic, store away from water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
(R)-(-)-Tetrahydrofurfurylamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors.
Solubility
Fully miscible with water.
Notes
Hygroscopic, store away from water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Liu, G. et al. Discovery of Potent, Selective, Orally Bioavailable Stearoyl-CoA Desaturase 1 Inhibitors. J. Med. Chem. 2007, 50 (13), 3086-3100.
- Piotr Przybylski; Magdalena Włodarz; Bogumil Brzezinski; Franz Bartl. Spectroscopic studies and PM5 semiempirical calculations of tautomeric forms of gossypol schiff base with (R)-tetrahydrofurfurylamine. Journal of Molecular Structure. 2004, 691 (1-3), 227-234.