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Thermo Scientific Chemicals
Arbutin, 98+%
CAS: 497-76-7 | C12H16O7 | 272.25 g/mol
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Catalog number L14945.03
also known as L14945-03
Price (EUR)
24,80
Each
Quantity:
1 g
Price (EUR)
24,80
Each
Chemical Identifiers
CAS497-76-7
IUPAC Name2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
Molecular FormulaC12H16O7
InChI KeyBJRNKVDFDLYUGJ-UHFFFAOYNA-N
SMILESOCC1OC(OC2=CC=C(O)C=C2)C(O)C(O)C1O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to pale cream
FormPowder or crystalline powder
Assay (HPLC)≥98.0%
Identification (FTIR)Conforms
Melting Point (clear melt)196.0-204.0°C
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Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Also used in sed as a skin-lightening agent in cosmetic products.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Also used in sed as a skin-lightening agent in cosmetic products.
Solubility
Soluble in water (50 mg/ml), methanol and dimethyl sulfoxide.
Notes
Hygroscopic, store away from water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
Arbutin, a glycosylated hydroquinone, is used in studies on melanin biosynthesis and as an inhibitor to identify, differentiate and characterize tyrosinase(s). Also used in sed as a skin-lightening agent in cosmetic products.
Solubility
Soluble in water (50 mg/ml), methanol and dimethyl sulfoxide.
Notes
Hygroscopic, store away from water/moisture. Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Hsiou-Yu Ding; Te-Sheng Chang; Hung-Chang Shen; Sorgan Shou-Ku Tai. Murine tyrosinase inhibitors from Cynanchum bungei and evaluation of in vitro and in vivo depigmenting activity. Experimental Dermatology.2011, 20(9), 720-724.
- Sang Mi An; Jae-Sook Koh; Yong Chool Boo. p-coumaric acid not only inhibits human tyrosinase activity in vitro but also melanogenesis in cells exposed to UVB. Phytotherapy Research.2010, 24(8), 1175-1180.