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Thermo Scientific Chemicals
1-Boc-isonipecotic acid, 98+%
CAS: 84358-13-4 | C11H19NO4 | 229.28 g/mol
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Catalog number L17527.06
also known as L17527-06
Price (EUR)
117,00
Each
Quantity:
5 g
Price (EUR)
117,00
Each
Chemical Identifiers
CAS84358-13-4
IUPAC Name1-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid
Molecular FormulaC11H19NO4
InChI KeyJWOHBPPVVDQMKB-UHFFFAOYSA-N
SMILESCC(C)(C)OC(=O)N1CCC(CC1)C(O)=O
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Assay (Silylated GC)≥98.0%
Appearance (Color)White
Assay (Aqueous acid-base Titration)≥98.0 to ≤102.0%
Melting Point (clear melt)148.0-154.0?C
It is a pharmaceutical intermediate. he camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is a pharmaceutical intermediate. he camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.
Solubility
Insoluble in water.
Notes
Store in cool dry conditions in well sealed containers. Incompatible with strong oxidizing agents.
It is a pharmaceutical intermediate. he camptothecin ester of isonipecotic acid is installed on a triazine dendrimer intermediate obtained through an iterative, scalable route to ultimately yield cationic and PEGylated targets with activities in cell culture comparable to free drug.
Solubility
Insoluble in water.
Notes
Store in cool dry conditions in well sealed containers. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Vincent J. Venditto.; Kimberly Allred.; Clinton D. Allred.; Eric E. Simanek. Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: a general strategy toward drug delivery vehicles.Chem. Commun. 2009, (37),5541-5542 .
- Pavol Zlatoidsky.; Tibor Maliar. Synthesis and structure-activity relationship study of the new set of trypsin-like proteinase inhibitors. European Journal of Medicinal Chemistry. 1999, 34 (12),1023-1034 .