2-Thiouracil, 99%, Thermo Scientific Chemicals

Name: 2-Thiouracil, 99%, Thermo Scientific Chemicals
SKU: 151841000

2-Thiouracil, Thiouracil or 4-Hydroxy-2-mercaptopyrimidine, CAS # 141-90-2, is the modified analog of the nucleotide base, uracil.

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Catalog Number	Quantity	Packaging
151841000	100g	Plastic bottle
151845000	500g	Plastic bottle

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Catalog number 151841000

Price (EUR)

Quantity:

100g

Packaging:

Plastic bottle

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Chemical Identifiers

CAS141-90-2

IUPAC Name2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one

Molecular FormulaC4H4N2OS

InChI KeyZEMGGZBWXRYJHK-UHFFFAOYSA-N

SMILESO=C1NC(=S)NC=C1

Specifications

Specification Sheet

HPLC>=98.0 %

Appearance (Color)White to light yellow

Infrared spectrumConforms

Loss on drying=<0.5 % (105°C, 3 h)

Appearance of solution(0.5% in 1M NaOH) Clear to light hazy

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

• 2-Thiouracil (Thiouracil or 4-Hydroxy-2-mercaptopyrimidine) is a nucleotide analog with a C-2 thioxo substitution
• 2-Thiouracil is a melanocyte suppressor and thyroid inhibitor

Applications
• 2-Thiouracil can be used to inhibit nitric oxide synthase and suppresses nitric oxide signaling in vitro
• 2-Thiouracil can be used for labeling of RNA in vitro
• 2-Thiouracil is intended for research applications only

RUO – Research Use Only

Literature references

Yang, W.; Shen, Z.; Wen, S.; Wang, W.; Hu, M. Mechanisms of multiple neurotransmitters in the effects of Lycopene on brain injury induced by Hyperlipidemia. Lipids Health Dis. 2018, 17(1), 13. Erratum in: Lipids Health Dis. 2018, 17 (1), 65.

Wauters, J.; Van, Meulebroek L.; Fichant, E.; Delahaut, P.; Vanhaecke, L. Discrimination between Synthetically Administered and Endogenous Thiouracil Based on Monitoring of Urine, Muscle, and Thyroid Tissue: An in Vivo Study in Young and Adult Bovines. J Agric Food Chem. 2017, 65(30), 6231-6239.