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Fumonisin B2, 96+%, Thermo Scientific Chemicals
Catalog number: 328260010
1 mg, Each
Thermo Scientific Chemicals
Fumonisin B2, 96+%, Thermo Scientific Chemicals
Catalog number: 328260010
1 mg, Each
Quantity
Catalog number: 328260010
Price (EUR)
389,82 Online price
438,00
Each
Quantity
-
Chemical Identifiers
CAS
116355-84-1
Specifications
Specification SheetHPLC
>=96.0 %
Appearance (Color)
White to light yellow to brown
Appearance (Form)
Solid
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
• Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)
Applications
• In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
• It can inhibit de novo sphingolipid biosynthesis
• It is also considered an Aspergillus metabolite
• It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
• It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 1
Acute dermal toxicity
Category 1
Acute Inhalation Toxicity - Dusts and Mists
Category 1
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Carcinogenicity
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
H300 + H310 + H330 - Fatal if swallowed, in contact with skin or if inhaled
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
H351 - Suspected of causing cancer
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician