Thermo Scientific Chemicals

Lovastatin, 98%

Catalog number: 458830050
5 g, Each
Thermo Scientific Chemicals

Lovastatin, 98%

Catalog number: 458830050
5 g, Each
Quantity
Catalog number: 458830050
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
75330-75-5
IUPAC Name
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
Molecular Formula
C24H36O5
InChI Key
PCZOHLXUXFIOCF-BXMDZJJMSA-N
SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
Appearance (Color)
White to light yellow
Appearance (Form)
Powder
Infrared spectrum
Conforms
HPLC
>=97.5 %

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Applications

• It blocks product ion of mevalonate, a critical compound in the production of cholesterol and isoprenoids

• It can increase cellular resistance to anticancer agents such as doxorubicin • It can induce apoptosis in myeloma cells

• It can cause cell cycle arrest in G1 and G2/M phase

• It also blocks PDGF receptor tyrosine phosphorylation and MAP kinase activation by PDGF

RUO – Research Use Only

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    Frequently asked questions (FAQs)

    Citations & References

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Sensitization
    Category 1
    Carcinogenicity
    Category 2
    Reproductive Toxicity
    Category 2
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H317 - May cause an allergic skin reaction

    H351 - Suspected of causing cancer

    H361d - Suspected of damaging the unborn child

    Precautionary Statements

    P201 - Obtain special instructions before use

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P308 + P313 - IF exposed or concerned: Get medical advice/attention