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Lovastatin, 98%
Catalog number: 458830050
5 g, Each
Thermo Scientific Chemicals
Lovastatin, 98%
Catalog number: 458830050
5 g, Each
Quantity
Catalog number: 458830050
Price (EUR)
64,71 Online price
71,90
Each
Quantity
-
Chemical Identifiers
CAS
75330-75-5
IUPAC Name
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
Molecular Formula
C24H36O5
InChI Key
PCZOHLXUXFIOCF-BXMDZJJMSA-N
SMILES
CC[C@H](C)C(=O)O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12
Specifications
Specification SheetAppearance (Color)
White to light yellow
Appearance (Form)
Powder
Infrared spectrum
Conforms
HPLC
>=97.5 %
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Applications
• It blocks product ion of mevalonate, a critical compound in the production of cholesterol and isoprenoids
• It can increase cellular resistance to anticancer agents such as doxorubicin • It can induce apoptosis in myeloma cells
• It can cause cell cycle arrest in G1 and G2/M phase
• It also blocks PDGF receptor tyrosine phosphorylation and MAP kinase activation by PDGF
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Sensitization
Category 1
Carcinogenicity
Category 2
Reproductive Toxicity
Category 2
Label Elements
Signal Word
Warning
Hazard Statements
H317 - May cause an allergic skin reaction
H351 - Suspected of causing cancer
H361d - Suspected of damaging the unborn child
Precautionary Statements
P201 - Obtain special instructions before use
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P308 + P313 - IF exposed or concerned: Get medical advice/attention