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3-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals
Catalog number: A12866.22
100 g, Each
Thermo Scientific Chemicals
3-Hydroxy-4-methoxybenzaldehyde, 98%, Thermo Scientific Chemicals
Catalog number: A12866.22
100 g, Each
Quantity
Catalog number: A12866.22
also known as A12866-22
Price (EUR)
109,80 Online price
122,00
Each
Quantity
-
Chemical Identifiers
CAS
621-59-0
IUPAC Name
3-hydroxy-4-methoxybenzaldehyde
Molecular Formula
C8H8O3
InChI Key
JVTZFYYHCGSXJV-UHFFFAOYSA-N
SMILES
COC1=CC=C(C=O)C=C1O
Specifications
Specification SheetForm
Crystals or powder or crystalline powder
Melting Point (clear melt)
111.0-117.0°C
Appearance (Color)
White to cream to gray to pale brown
Assay (GC)
≥97.5%
Description
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.
Solubility
Soluble in acetone and methanol.
Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
3-Hydroxy-4-methoxybenzaldehyde acts as a precursor for the stereoselective synthesis of the anticancer drug (Z)-combretastatin A-4 and glycitein. It also used as an important raw material for the preparation of morphine. Further, it is involved in the preparation of Schiff- bases by reacting with furan-2-carboxylic acid hydrazide and thiophene-2-carboxylic acid hydrazide. In addition to this, it is used to prepare (Z)-2-(3-hydroxy-4-methoxybenzylidene)-1-azabicyclo[2.2.2]octan-3-one by reacting with with1-azabicyclo[2.2.2]octan-3-one.
Solubility
Soluble in acetone and methanol.
Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Warning
Hazard Statements
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary Statements
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing