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Guanidine hydrochloride, 98%, Thermo Scientific Chemicals
Catalog number: A13543.30
250 g, Each
Thermo Scientific Chemicals
Guanidine hydrochloride, 98%, Thermo Scientific Chemicals
Catalog number: A13543.30
250 g, Each
Quantity
Catalog number: A13543.30
also known as A13543-30
Price (EUR)
27,09 Online price
30,10
Each
Quantity
-
Chemical Identifiers
CAS
50-01-1
IUPAC Name
hydrogen guanidine chloride
Molecular Formula
CH6ClN3
InChI Key
PJJJBBJSCAKJQF-UHFFFAOYSA-N
SMILES
[H+].[Cl-].NC(N)=N
Specifications
Specification SheetWater Content (Karl Fischer Titration)
<1.0%
Melting Point (clear melt)
180-189°C
Appearance (Color)
White
Comment
Anticaking agent (SiO2): ≤0.4%
Identification (FTIR)
Conforms
Description
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2- amino -6- methyl-pyrimidine and 2-amino -4,6 - dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Guanidine hydrochloride is the hydrochloride salt of guanidine, an acetylcholine releasing agent
- It is a normal product of protein metabolism and is sometimes used for pyrimidine synthesis
Application
- Guanidine hydrochloride is a powerful denaturant, useful for taking nucleic acids (DNA and RNA) and proteins out of their native conformation
- Guanidine hydrochloride acts as a strong organic base at physiological pH
- It is suitable for use in protein and nucleic acid purification protocols
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Acute Inhalation Toxicity - Dusts and Mists
Category 4
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Label Elements
Signal Word
Warning
Hazard Statements
H302 + H332 - Harmful if swallowed or if inhaled
H315 - Causes skin irritation
H319 - Causes serious eye irritation
EU Specific Hazard Statements
May form combustible dust concentrations in air
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing
P312 - Call a POISON CENTER or doctor if you feel unwell
P337 + P313 - If eye irritation persists: Get medical advice/attention