trans-3-(3-Pyridyl)acrylic acid is a useful synthetic intermediate. It is also used to prepare aminomethyl benzimidazoles, which acts as an inhibitor of gelatinase B. Further, it is used in the preparation of aminopyridines as antibacterial enoyl acyl carrier protein reductase inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
trans-3-(3-Pyridyl)acrylic acid is a useful synthetic intermediate. It is also used to prepare aminomethyl benzimidazoles, which acts as an inhibitor of gelatinase B. Further, it is used in the preparation of aminopyridines as antibacterial enoyl acyl carrier protein reductase inhibitors.
Notes
Incompatible with oxidizing agents, acids and bases.
RUO – Research Use Only
General References:
- Singha, D. K.; Mahata, P. Luminescent coordination polymer-fullerene composite as a highly sensitive and selective optical detector for 2,4,6-trinitrophenol (TNP). RSC Adv. 2015, 5 (36), 28092-28097.
- Sun, X.; Zhang, L.; Zhang, H.; Qian, H.; Ji, J.; Tang, L.; Li, Z.; Zhang, G. Electrochemical detection of 8-hydroxy-2'-deoxyguanosine as a biomarker for oxidative DNA damage in HEK293 cells exposed to 3-chloro-1,2-propanediol. Anal. Methods 2015, 7 (16), 6664-6671.