Thermo Scientific Chemicals

p-Toluenesulfonyl isocyanate, 95%, Thermo Scientific Chemicals

Catalog number: A17492.36
500 g, Each
Thermo Scientific Chemicals

p-Toluenesulfonyl isocyanate, 95%, Thermo Scientific Chemicals

Catalog number: A17492.36
500 g, Each
Quantity
Catalog number: A17492.36
also known as A17492-36
Price (EUR)
Price: 136,00
Your price:
Quantity
-

Chemical Identifiers

CAS
4083-64-1
Form
Liquid
Refractive Index
1.5320-1.5380 @ 20?C
Appearance (Color)
Clear colorless to pale yellow
Assay (GC)
≥94.0%
Identification (FTIR)
Conforms

Description

It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

Solubility
Reacts with water.

Notes
Keep away from alcohols, strong bases, amines, strong oxidizing agents.
RUO – Research Use Only

Figures

Documents & Downloads

Certificates

    Frequently asked questions (FAQs)

    Citations & References

    Search citations by name, author, journal title or abstract text

    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Respiratory Sensitization
    Category 1
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled

    H335 - May cause respiratory irritation

    EU Specific Hazard Statements

    EUH014 - Reacts violently with water

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P284 - Wear respiratory protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P312 - Call a POISON CENTER or doctor if you feel unwell