4-(Trifluoromethyl)benzeneboronic acid, 98%
4-(Trifluoromethyl)benzeneboronic acid, 98%
4-(Trifluoromethyl)benzeneboronic acid, 98%
Thermo Scientific Chemicals

4-(Trifluoromethyl)benzeneboronic acid, 98%

CAS: 128796-39-4 | C7H6BF3O2 | 189.93 g/mol
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1 g
5 g
25 g
Catalog number B22374.03
also known as B22374-03
Price (EUR)
47,80
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Quantity:
1 g
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Price (EUR)
47,80
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Specifications
Beilstein3544189
CAS128796-39-4
Chemical Name or Material4-(Trifluoromethyl)benzeneboronic acid
EINECS Number000-000-0
Formula Weight189.93
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4-(Trifluoromethyl)benzeneboronic acid is used of this drug is to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-(Trifluoromethyl)benzeneboronic acid is used of this drug is to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones.

Solubility
Soluble in DMSO, not in water

Notes
Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Cao KS.; Bian HX.; Zheng WH. Mild arylboronic acid catalyzed selective [4 + 3] cycloadditions: access to cyclohepta[b]benzofurans and cyclohepta[b]indoles. Org Biomol Chem. 2015, 13, (23), 6449-52.
  2. Maki T.; Ishihara K.; Yamamoto H. 4,5,6,7-Tetrachlorobenzo[d][1,3,2]dioxaborol- 2-ol as an effective catalyst for the amide condensation of sterically demanding carboxylic acids. Org Lett.2006, 8, (7), 1431-4.
  3. For phosphine-free palladium-catalyzed Suzuki coupling with aryl halides, see: J. Org. Chem., 59, 5034 (1994).