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Ethyl iodoacetate, 98%, Thermo Scientific Chemicals
Ethyl iodoacetate, 98%, Thermo Scientific Chemicals
Ethyl iodoacetate, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Ethyl iodoacetate, 98%, Thermo Scientific Chemicals

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Catalog number B24177.06
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5 g
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Chemical Identifiers
CAS623-48-3
IUPAC Nameethyl 2-iodoacetate
Molecular FormulaC4H7IO2
InChI KeyMFFXVVHUKRKXCI-UHFFFAOYSA-N
SMILESCCOC(=O)CI
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
StabilizerCopper wire
Appearance (Color)Clear colorless or pale yellow to orange
Assay (GC)≥97.0%
Refractive Index1.5020-1.5070 @ 20?C
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Ethyl iodoacetate was used in the synthesis of trans-2,3-disubstituted indolines by reacting with 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ethyl iodoacetate was used in the synthesis of trans-2,3-disubstituted indolines by reacting with 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade.

Solubility
Insoluble in water.

Notes
Light sensitive. Store in dark. Storage temperature is 2-8°C. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. François Brucelle; Philippe Renaud. Synthesis of a leucomitosane via a diastereoselective radical cascade. Journal of Organic Chemistry. 2013, 78, (12), 6245-6252.
  2. Pier Giorgio Cozzi; Alessandro Mignogna and Paola Vicennati. Dimethylzinc-Mediated, Oxidatively Promoted Reformatsky Reaction of Ethyl Iodoacetate with Aldehydes and Ketones. Advanced Synthesis & Catalysis. 2008, 300, (7-8), 975-978.