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Methoxycarbonylsulfenyl chloride, 95%, Thermo Scientific Chemicals
Catalog number: L04350.03
1 g, Each
Thermo Scientific Chemicals
Methoxycarbonylsulfenyl chloride, 95%, Thermo Scientific Chemicals
Catalog number: L04350.03
1 g, Each
Quantity
Catalog number: L04350.03
also known as L04350-03
Price (EUR)
36,94 Online price
41,50
Each
Quantity
-
Chemical Identifiers
CAS
26555-40-8
IUPAC Name
(chlorosulfanyl)(methoxy)methanone
Molecular Formula
C2H3ClO2S
InChI Key
TXJXPZVVSLAQOQ-UHFFFAOYSA-N
SMILES
COC(=O)SCl
Specifications
Specification SheetAppearance (Color)
Clear colorless to yellow
Form
Liquid
Assay (GC)
>94.0%
Refractive Index
1.4795-1.4865 @ 20?C
Description
Methoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.
Solubility
Miscible with dichlormethane.
Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Methoxycarbonylsulfenyl chloride is used to prepare 3-[(methoxycarbonyl)dithio]-L-alanine by reacting with L-cysteine. Further, it is used in the synthesis of 3-2 pyridinyldithio propanoic acid hydrazide (PDPH). It serves as an important heterobifunctional crosslinker, which is a crosslinker used to make macromolecule-drug conjugates.
Solubility
Miscible with dichlormethane.
Notes
Moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Flammable liquids
Category 3
Skin Corrosion/Irritation
Category 1
Serious Eye Damage/Eye Irritation
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H314 - Causes severe skin burns and eye damage
Physical Hazards
H226 - Flammable liquid and vapor
Precautionary Statements
P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 - Wear eye protection/ face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P310 - Immediately call a POISON CENTER or doctor/physician