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Thermo Scientific Chemicals
3-(Trimethylsilyl)propargyl alcohol, 98%
CAS: 5272-36-6 | C6H12OSi | 128.25 g/mol
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Catalog number L09649.03
also known as L09649-03
Price (EUR)
28,00
Each
Quantity:
1 g
Price (EUR)
28,00
Each
Chemical Identifiers
CAS5272-36-6
Specifications
Specification Sheet
Specification SheetRefractive Index1.4490-1.4530 @ 20?C
Appearance (Color)Clear, colorless to pale yellow
Identification (FTIR)Conforms
FormLiquid
Assay (GC)≥98.0%
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
Solubility
Not miscible with water.
Notes
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.
3-(Trimethylsilyl)propargyl alcohol is used as a reagent to synthesize Isbogrel, a Thromboxane A 2 (TXA 2) synthase inhibitor and also a TXA 2 receptor antagonist that has potential to treat asthma.
Solubility
Not miscible with water.
Notes
Moisture Sensitive. Store away from moisture and oxidizing agents. Protect from heat. Store under dry inert gas. Protect from humidity and water. Incompatible with oxidizing agents, heat and moisture.
RUO – Research Use Only
General References:
- Reduction with Sodium bis(2-methoxyethoxy) aluminum hydride, A13292, gives stereoselectively (E)-3-TMS-2-propen-1-ol: Org. Synth. Coll., 7, 524 (1990). For titanocene dichloride-promoted hydromagnesiation reaction with isobutylmagnesium bromide, see: Org. Synth. Coll., 8, 507, (1993). See Bis(cyclopentadienyl) titanium dichloride, A11456.