3-Chlorobenzyl bromide was used in the synthesis of symmetrical and unsymmetrical benzyl thioethers. It was used as starting reagent during the synthesis of 1-(3-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole dihydrochloride.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
El bromuro de 3-clorobenzilo se utilizó en la síntesis de tioéteres de bencilo simétricos y asimétricos. Se utilizó como reactivo inicial durante la síntesis de 1-(3-clorobenzil)-2-(pirrolidin-1-ilmetil)-1H-bencimidazol diclorhidrato.
Solubilidad
Se descompone en agua.
Notas
Almacenar a temperatura ambiente. Manténgase lejos de los agentes oxidantes.
RUO – Research Use Only
- Leonardo Pisani;Giovanni Muncipinto; Teresa Fabiola Miscioscia; Orazio Nicolotti; Francesco Leonetti; Marco Catto; Carla Caccia; Patricia Salvati; Ramon Soto-Otero; Estefania Mendez-Alvarez; Celine Passeleu; Angelo Carotti. Discovery of a Novel Class of Potent Coumarin Monoamine Oxidase B Inhibitors: Development and Biopharmacological Profiling of 7-[(3-Chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one Methanesulfonate (NW-1772) as a Highly Potent, Selective, Reversible, and Orally Active Monoamine Oxidase B Inhibitor. J. Med. Chem. 2009, 52 (21), 6685-6706.