Clorhidrato de L-homoarginina, 98+ %, Thermo Scientific Chemicals
Clorhidrato de L-homoarginina, 98+ %, Thermo Scientific Chemicals
Clorhidrato de L-homoarginina, 98+ %, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Clorhidrato de L-homoarginina, 98+ %, Thermo Scientific Chemicals

CAS: 1483-01-8 | C7H17ClN4O2 | 224.689 g/mol
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Cantidad:
1 g
5 g
25 g
Número de catálogo H27387.06
también denominado H27387-06
Precio (EUR)
242,65
Online exclusive
269,00
Ahorro 26,35 (10%)
Each
Cantidad:
5 g
Pedido a granel o personalizado
Precio (EUR)
242,65
Online exclusive
269,00
Ahorro 26,35 (10%)
Each
Identificadores químicos
CAS1483-01-8
IUPAC Namehydrogen 2-amino-6-[(diaminomethylidene)amino]hexanoic acid chloride
Molecular FormulaC7H17ClN4O2
InChI KeyYMKBVNVCKUYUDM-UHFFFAOYNA-N
SMILES[H+].[Cl-].NC(CCCCN=C(N)N)C(O)=O
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EspecificacionesSpecification SheetHoja de especificaciones
FormCrystals or powder or crystalline powder or granules
Appearance (Color)White
Assay from Supplier's CofA≥97.5%
Optical Rotation18.0 ± 2.0° (C=1 in 1N HCl)
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
An inhibitor of alkaline phosphatase isoenzymes. It is also an inhibitor of cellular transport of arginine by a sodium-independent high affinity y+ transporter. The substitution of homoarginine for arginine or lysine renders proteins resistant to proteolysis by trypsin. Arginine residues are often located at the active centers of proteins and enzymes. Replacing these arginines with homoarginine can elucidate protein function and structural requirements.

Solubility
Soluble in water(50 mg/mL).

Notes
Moisture Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents. Refrigerated(2-7°C).
RUO – Research Use Only

General References:

  1. Ambar K Choudhury et. al. Synthesis of proteins containing modified arginine residues. Biochemistry (Washington). 2007, 46(13),4066-4076 .
  2. E. A. Bell. The isolation of l-homoarginine from seeds of Lathyrus cicera. Biochem J.. 1962 , 85(1),91-93.