5'-O-(terc-butildimetilsilil)timidina, + 97 %, Thermo Scientific Chemicals
5'-O-(terc-butildimetilsilil)timidina, + 97 %, Thermo Scientific Chemicals
5'-O-(terc-butildimetilsilil)timidina, + 97 %, Thermo Scientific Chemicals
Thermo Scientific Chemicals

5'-O-(terc-butildimetilsilil)timidina, + 97 %, Thermo Scientific Chemicals

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Número de catálogoCantidad
H52301.03
también denominado H52301-03
1 g
Número de catálogo H52301.03
también denominado H52301-03
Precio (EUR)
111,00
Each
Cantidad:
1 g
Pedido a granel o personalizado
Precio (EUR)
111,00
Each
Identificadores químicos
CAS40733-28-6
IUPAC Name1-[(2R,4S,5R)-5-{[(tert-butyldimethylsilyl)oxy]methyl}-4-hydroxyoxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Molecular FormulaC16H28N2O5Si
InChI KeyIJWIJLIIOKZJMS-YNEHKIRRSA-N
SMILESCC1=CN([C@H]2C[C@H](O)[C@@H](CO[Si](C)(C)C(C)(C)C)O2)C(=O)NC1=O
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EspecificacionesSpecification SheetHoja de especificaciones
FormPowder
Assay from Supplier's CofA≥97.0%
CommentIdentification by NMR: Conforms
Appearance (Color)White to off-white
Loss on Drying≤1.0%
5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
La 5′-o-(terc-butildimetilsilil)timidina se utiliza como intermedio farmacéutico.

Notas
Estable en las condiciones de almacenamiento recomendadas. Incompatible con los agentes oxidantes.
RUO – Research Use Only

General References:

  1. Masayoshi Takase; Masahiko Inouye. Highly efficient recognition of native TpT by artificial ditopic hydrogen-bonding receptors possessing a conformationally well-defined linkage. J. Org. Chem. 2003, 68, (3),1134-1137
  2. Yixin Lu. Recent advances in the stereocontrolled synthesis of antisense phosphorothioates. Mini Reviews in Medicinal Chemistry. 2006, 6, (3),319-330