Thermo Scientific Chemicals

Indomethacin, 99+%, Thermo Scientific Chemicals

Número de catálogo: J63255.06
5 g, Each
Thermo Scientific Chemicals

Indomethacin, 99+%, Thermo Scientific Chemicals

Número de catálogo: J63255.06
5 g, Each
Cantidad
Informational:Con fines informativos:Este producto químico puede requerir que obtengamos información adicional para nuestros registros de cumplimiento normativo y químico. Si es necesario, nos pondremos en contacto con usted para obtener esta información una vez que haya realizado su pedido.
Número de catálogo: J63255.06
también denominado J63255-06
Precio (EUR)
Precio: 56,60
Precio en línea: 50,94
Su precio:
Cantidad
-

Descripción

Non-selective cyclooxygenase inhibitorIndomethacin acts as an antiinflammatory, antipyretic and analgesic. It serves as an inhibitor cyclooxygenase such as Cox-1 and Cox-2. In addition to this, it is used as a prescription medication in order to reduce fever, stiffness, swelling and pain.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Indomethacin is a synthetic NSAID of the indole family that inhibits cyclooxygenase and reduces prostaglandin and pyrogen release
• Indomethacin may suppress the multi-drug resistant transporter and thereby increase the efficacy of antineoplastics
• Indomethacin activates phosphatases that inhibit signaling pathways associated with cancer cell migration and proliferation
Applications
• Indomethacin may be used for the laboratory study of cancer cell proliferation, tumorigenesis and drug interactions
• Indomethacin may be used for laboratory study of the effect of inhibiting the multi-drug resistance transporter, or for downregulation of survival signaling in cells via survivin
RUO – Research Use Only

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    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 2
    Skin Sensitization
    Category 1
    Reproductive Toxicity
    Category 1B
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H300 - Fatal if swallowed

    H317 - May cause an allergic skin reaction

    H360FD - May damage fertility. May damage the unborn child

    Precautionary Statements

    P201 - Obtain special instructions before use

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P308 + P313 - IF exposed or concerned: Get medical advice/attention

    P405 - Store locked up

    Additional EU labelling

    Restricted to professional users