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Etoposide, Thermo Scientific Chemicals
Número de catálogo: J63651.MC
100 mg, Each
Thermo Scientific Chemicals
Etoposide, Thermo Scientific Chemicals
Número de catálogo: J63651.MC
100 mg, Each
Cantidad
Número de catálogo: J63651.MC
también denominado J63651-MC
Precio (EUR)
187,20 Precio en línea
208,00
Each
Cantidad
-
Identificadores químicos
CAS
33419-42-0
Especificaciones
Hoja de especificacionesAssay from Suppliers CofA
≥95.0%
Form
Powder or crystals or crystalline powder
Infrared spectrum
Conforms
Descripción
Etoposide is used as a inhibits DNA synthesis and is very active against cells in the late S and G2 phases of the cell cycle. Etoposide was reported to be used to serum starve Saos-2 M5(p53-/-) cells which were transfected by electroporation with indicated expression plasmids for flag-E2F1 and myc-EBNA3C for selection of colony forming units, thus studying the blocking effect of EBV Nuclear Antigen 3C on E2F1 Mediated Apoptosis Induced by the DNA Damage Response.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Etoposide is used as a inhibits DNA synthesis and is very active against cells in the late S and G2 phases of the cell cycle. Etoposide was reported to be used to serum starve Saos-2 M5(p53-/-) cells which were transfected by electroporation with indicated expression plasmids for flag-E2F1 and myc-EBNA3C for selection of colony forming units, thus studying the blocking effect of EBV Nuclear Antigen 3C on E2F1 Mediated Apoptosis Induced by the DNA Damage Response.
Solubility
Insoluble in water.
Notes
Store solutions in DMSO at 4°C. For long term storage prepare aliquots and store at -20°C.
Etoposide is used as a inhibits DNA synthesis and is very active against cells in the late S and G2 phases of the cell cycle. Etoposide was reported to be used to serum starve Saos-2 M5(p53-/-) cells which were transfected by electroporation with indicated expression plasmids for flag-E2F1 and myc-EBNA3C for selection of colony forming units, thus studying the blocking effect of EBV Nuclear Antigen 3C on E2F1 Mediated Apoptosis Induced by the DNA Damage Response.
Solubility
Insoluble in water.
Notes
Store solutions in DMSO at 4°C. For long term storage prepare aliquots and store at -20°C.
RUO – Research Use Only
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Seguridad y manipulación
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Carcinogenicity
Category 1A
Label Elements
Signal Word
Danger
Hazard Statements
H302 - Harmful if swallowed
H350 - May cause cancer
Precautionary Statements
P201 - Obtain special instructions before use
P264 - Wash face, hands and any exposed skin thoroughly after handling
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P312 - Call a POISON CENTER or doctor if you feel unwell
Additional EU labelling
Restricted to professional users