It is used as a reagent in the preparation of4-(1,2,4-oxadiazol-5-yl)piperidine-1-carboxamides as antiproliferative tubulin inhibitors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Aplicaciones
Se utiliza como reactivo en la preparación de 4-(1,2,4-oxadiazol-5-il)piperidina-1-carboxamidas como inhibidores antiproliferativos de la tubulina.
Solubilidad
Soluble en agua a 20 °C 20 g/l.
Notas
Almacenar alejado de agentes oxidantes. Mantener el recipiente bien cerrado en un lugar fresco, seco y bien ventilado. Proteger del calor. Mantener refrigerado.
RUO – Research Use Only
General References:
- Hiroshi Kawai, et al. Novel Endogenous 1,2,3 ,4-Tetrahydroisoquinoline Derivatives: Uptake by Dopamine Transporter and Activity to Induce Parkinsonism.J. Neurochem.,1998,70(2), 745-751.
- Estefanía Méndez-Álvarez, et al. Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke.Life Sci.,1997,60(19), 1719-1727.