Glicina éster de tert-butilo, 97 %, Thermo Scientific Chemicals

Glycine tert-butyl ester is used in the preparation of Schiff base by reacting with benzophenone. The resultant Schiff base undergoes asymmetric alkylation with arylmethyl bromides in the presence of O-allyl-N-(9-anthracenylmethyl)cinchonidinium bromide as chiral phase transfer catalyst to give guanidine-containing pentacyclic compound.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Aplicaciones
El éster tert-butilo de glicina se utiliza en la preparación de la base de Schiff reaccionando con benzofenona. La base de Schiff resultante sufre alquilación asimétrica con bromuros de arilmetil en presencia de bromuro de o-alilo-N-(9-antracenilmetil)cinconidinium como catalizador de transferencia de fase quiral para dar compuesto pentacíclico que contiene guanidina.

Solubilidad
Miscible con acetona y metanol. Ligeramente miscible con etanol. Inmiscible con agua.

Notas
Sensible al aire. Almacenar en lugar fresco. Incompatible con agentes oxidantes fuertes.