A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease. For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
Especificaciones
Conjugado
Tb (Terbium)/Lanthanide Chelates
Cantidad
25 μg
Excitación/emisión
340⁄490, 520
Reactividad
Human
Condiciones de envío
Dry Ice
Presentación de datos
End Point
Reactividad abrv
Hu
Gen diana
Ser/Thr Kinases
Línea de productos
LanthaScreen™
Contenido y almacenamiento
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.
Figuras
Documentos y descargas
Certificados
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