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4-Epianhydrotetracycline hydrochloride, can be used as a secondary standard
Catalog number: 233115000
500mg, Glass bottle, Each
Thermo Scientific Chemicals
4-Epianhydrotetracycline hydrochloride, can be used as a secondary standard
Catalog number: 233115000
500mg, Glass bottle, Each
Quantity
Packaging
Catalog number: 233115000
Price (EUR)
793,80 Online price
882,00
Each
Quantity
-
Chemical Identifiers
CAS
4465-65-0
IUPAC Name
4-(dimethylamino)-1,10,11,12a-tetrahydroxy-6-methyl-3,12-dioxo-3,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide hydrochloride
Molecular Formula
C22H23ClN2O7
InChI Key
SPFAOPCHYIJPHJ-UHFFFAOYNA-N
SMILES
Cl.CN(C)C1C2CC3=C(C(O)=C4C(O)=CC=CC4=C3C)C(=O)C2(O)C(O)=C(C(N)=O)C1=O
Specifications
Specification SheetInfrared spectrum
Conforms
Appearance (Color)
Orange
Appearance (Form)
Powder
Purity
>=80 % (as is, calculated)
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
- 4-Epianhydrotetracycline hydrochloride is a secondary degradation product formed by epimerization of tetracycline and dehydration at the C6 position to aromatize the B ring
- It has 250-fold higher toxicity than either tetracycline or doxycycline depending on the system under study
Applications
- 4-Epianhydrotetracycline hydrochloride is less toxic to E. coli, and thus suitable for use with vectors or systems designed upon elements of the (Tn10) tet operon of E. coli
- This compound is also used in veterinary medicine research and as a secondary standard for application in quality control in pharmaceutical laboratories
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Acute oral toxicity
Category 4
Serious Eye Damage/Eye Irritation
Category 2
Reproductive Toxicity
Category 2
Label Elements
Signal Word
Warning
Hazard Statements
H302 - Harmful if swallowed
H319 - Causes serious eye irritation
H361d - Suspected of damaging the unborn child
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
P312 - Call a POISON CENTER or doctor if you feel unwell