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Sodium glycocholate hydrate, 98%, Thermo Scientific Chemicals
Catalog number: 369460250
25 g, Glass bottle, Each
Thermo Scientific Chemicals
Sodium glycocholate hydrate, 98%, Thermo Scientific Chemicals
Catalog number: 369460250
25 g, Glass bottle, Each
Quantity
Packaging
Chemical Identifiers
CAS
207614-05-9
IUPAC Name
sodium 2-[(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanamido]acetate
Molecular Formula
C26H42NNaO6
InChI Key
OABYVIYXWMZFFJ-XIMBWSGONA-M
SMILES
[Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC(=O)NCC([O-])=O
Specifications
Specification SheetAppearance (Form)
Powder
Infrared spectrum
Conforms
Specific optical rotation
+28° to +31° (20°C, 589 nm) (c=1, H2O)
HPLC
>=97.5 %
Appearance (Color)
White to cream
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Sodium glycocholate hydrate is a conjugated bile salt
- It is an ionic detergent
Applications
- Sodium glycocholate hydrate is used to determine serum total bile acids by fluorimetric and enzymatic methods.
- It has also been used in in vitro studies to investigate its effect on micelle formation and solubilization of testosterone.
- This compound is considered a detergent used to solubilize fats for absorption.
- This chemical product is synthetically derived from a natural compound, cholic acid.
- Sodium glycocholate hydrate has been tested in the laboratory for its ability to form a liposomal delivery system to enhance oral insulin delivery. The in vitro results demonstrated that sodium glycocholate liposomes showed promising activity and can be useful to create a new approach to orally deliver insulin more efficiently.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Label Elements
Signal Word
Warning
Hazard Statements
H315 - Causes skin irritation
H319 - Causes serious eye irritation
Precautionary Statements
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P332 + P313 - If skin irritation occurs: Get medical advice/attention
P337 + P313 - If eye irritation persists: Get medical advice/attention