PCDNA3.1(-)⁄MYC-HIS ABC

Name: PCDNA3.1(-)&frasl;MYC-HIS ABC
SKU: 430029

Catalog number 430029

Price (EUR)

Specifications

Unit Size1 each

Citations & References (2)

Citations & References

Abstract

Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.

Authors:Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I,

Journal:Neuron

PubMed ID:12062018

'PQBP-1 was isolated on the basis of its interaction with polyglutamine tracts. In this study, using in vitro and in vivo assays, we show that the association between ataxin-1 and PQBP-1 is positively influenced by expanded polyglutamine sequences. In cell lines, interaction between the two molecules induces apoptotic cell death. ... More

Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase.

Authors:Failer BU, Braun N, Zimmermann H,

Journal:J Biol Chem

PubMed ID:12167635

We have isolated and characterized the cDNA encoding a Ca(2+)-dependent nucleoside diphosphatase (EC ) related to two secreted ATP- and ADP-hydrolyzing apyrases of the bloodsucking insects, Cimex lectularius and Phlebotomus papatasi. The rat brain-derived cDNA has an open reading frame of 1209 bp encoding a protein of 403 amino acids ... More