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6-Fluoro-2-methylquinoline, 98+%, Thermo Scientific Chemicals
Catalog number: A11469.22
100 g, Each
Thermo Scientific Chemicals
6-Fluoro-2-methylquinoline, 98+%, Thermo Scientific Chemicals
Catalog number: A11469.22
100 g, Each
Quantity
Catalog number: A11469.22
also known as A11469-22
Price (EUR)
931,83 Online price
1 047,00
Each
Quantity
-
Chemical Identifiers
CAS
1128-61-6
IUPAC Name
6-fluoro-2-methylquinoline
Molecular Formula
C10H8FN
InChI Key
GPIARMSVZOEZCV-UHFFFAOYSA-N
SMILES
CC1=CC=C2C=C(F)C=CC2=N1
Specifications
Specification SheetAppearance (Color)
White to pale cream to pale brown to gray
Form
Crystals or powder or crystalline powder
Assay (GC)
≥98.0%
Identification (FTIR)
Conforms
Melting Point (clear melt)
49.0-55.0?C
Description
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Bronsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
Solubility
Soluble in Chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Metal-free transfer hydrogenation of 6-fluoro-2-methylquinoline by employing several chiral Brønsted acid catalysts was carried out in combination with dihydropyridines as the hydride source in asymmetric metal-free synthesis of fluoroquinolones by organocatalytic hydrogenation. Hydrogenation product of 6-fluoro-2-methylquinoline is the key intermediate of the antibacterial agent.
Solubility
Soluble in Chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Warning
Hazard Statements
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Precautionary Statements
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing