Thermo Scientific Chemicals

o-Phenylenediamine, 98%, Thermo Scientific Chemicals

Catalog number: A11946.30
250 g, Each
Thermo Scientific Chemicals

o-Phenylenediamine, 98%, Thermo Scientific Chemicals

Catalog number: A11946.30
250 g, Each
Quantity
Catalog number: A11946.30
also known as A11946-30
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
95-54-5
IUPAC Name
benzene-1,2-diamine
Molecular Formula
C6H8N2
InChI Key
GEYOCULIXLDCMW-UHFFFAOYSA-N
SMILES
NC1=CC=CC=C1N
Appearance (Color)
White to pale brown
Assay (GC)
≥97.5%
Melting Point (clear melt)
99-104?C
Form
Crystals, flakes or pellets
Identification (FTIR)
Conforms

Description

o-phenylenediamine is used to prepare tiabendazole, pyrazinamide, morinamide, clemizole and chlormidazole. It is involved in the synthesis of benzimidazole by reacting with carboxylic acids and their derivatives. It is also used to prepare quinoxalinedione and mercaptoimidazoles by condensation with dimethyl oxalate and xanthate esters respectively. It reacts with nitrous acid to get benzotriazole, which finds application as a corrosion inhibitor. It is actively involved in the preparation of pharmaceuticals by reacting substituted o-phenylenediamine with various diketones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
o-phenylenediamine is used to prepare tiabendazole, pyrazinamide, morinamide, clemizole and chlormidazole. It is involved in the synthesis of benzimidazole by reacting with carboxylic acids and their derivatives. It is also used to prepare quinoxalinedione and mercaptoimidazoles by condensation with dimethyl oxalate and xanthate esters respectively. It reacts with nitrous acid to get benzotriazole, which finds application as a corrosion inhibitor. It is actively involved in the preparation of pharmaceuticals by reacting substituted o-phenylenediamine with various diketones.

Solubility
Soluble in alcohol, chloroform, ether, slightly soluble in water. Soluble in hot water.

Notes
Moisture and air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Acute oral toxicity
    Category 3
    Acute dermal toxicity
    Category 4
    Acute Inhalation Toxicity - Dusts and Mists
    Category 4
    Serious Eye Damage/Eye Irritation
    Category 2
    Skin Sensitization
    Category 1
    Germ Cell Mutagenicity
    Category 2
    Carcinogenicity
    Category 2
    Acute aquatic toxicity
    Category 1
    Chronic aquatic toxicity
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H301 - Toxic if swallowed

    H312 + H332 - Harmful in contact with skin or if inhaled

    H317 - May cause an allergic skin reaction

    H319 - Causes serious eye irritation

    H341 - Suspected of causing genetic defects

    H351 - Suspected of causing cancer

    H410 - Very toxic to aquatic life with long lasting effects

    EU Specific Hazard Statements

    May form combustible dust concentrations in air

    Precautionary Statements

    P273 - Avoid release to the environment

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water