Thermo Scientific Chemicals

Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate, Thermo Scientific Chemicals

Catalog number: A15682.0B
1000 g, Each
Thermo Scientific Chemicals

Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate, Thermo Scientific Chemicals

Catalog number: A15682.0B
1000 g, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: A15682.0B
also known as A15682-0B
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
501-53-1
IUPAC Name
benzyl carbonochloridate
Molecular Formula
C8H7ClO2
InChI Key
HSDAJNMJOMSNEV-UHFFFAOYSA-N
SMILES
ClC(=O)OCC1=CC=CC=C1
Refractive Index
1.5140-1.5200 @ 20?C
Identification (FTIR)
Conforms
Appearance (Color)
Clear colorless to pale yellow
Assay (GC)
≥94.0%
Form
Liquid

Description

Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

Solubility
Miscible with ether, acetone and benzene.

Notes
Store in cool place. Moisture sensitive.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Substances/mixtures corrosive to metal
    Category 1
    Acute Inhalation Toxicity - Vapors
    Category 4
    Skin Corrosion/Irritation
    Category 1
    Serious Eye Damage/Eye Irritation
    Category 1
    Skin Sensitization
    Category 1
    Carcinogenicity
    Category 1B
    Specific target organ toxicity - (single exposure)
    Category 3
    Acute aquatic toxicity
    Category 1
    Chronic aquatic toxicity
    Category 1
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H314 - Causes severe skin burns and eye damage

    H317 - May cause an allergic skin reaction

    H332 - Harmful if inhaled

    H335 - May cause respiratory irritation

    H350 - May cause cancer

    H410 - Very toxic to aquatic life with long lasting effects

    Physical hazards

    H290 - May be corrosive to metals

    EU Specific Hazard Statements

    Combustible liquid

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting

    P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician

    Additional EU labelling

    Restricted to professional users