Thermo Scientific Chemicals

Ellagic acid hydrate, 97%, may cont. up to 12% water, Thermo Scientific Chemicals

Catalog number: A15722.06
5 g, Each
Thermo Scientific Chemicals

Ellagic acid hydrate, 97%, may cont. up to 12% water, Thermo Scientific Chemicals

Catalog number: A15722.06
5 g, Each
Quantity
Catalog number: A15722.06
also known as A15722-06
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
476-66-4
IUPAC Name
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaene-3,10-dione
Molecular Formula
C14H6O8
InChI Key
AFSDNFLWKVMVRB-UHFFFAOYSA-N
SMILES
OC1=CC2=C3C(OC(=O)C4=CC(O)=C(O)C(OC2=O)=C34)=C1O
Appearance (Color)
White to cream to yellow to green to brown to grey
Comment
May contain up to 12% water.
Identification (FTIR)
Conforms
Water Content (Karl Fischer Titration)
≤12.0%
Form
Powder

Description

Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Ellagic acid used as selective, ATP-competitive inhibitor of casein kinase 2. Exhibits antitumor activity and inhibits glutathione S-transferase. It is also used as a Topo I and II, FGR, GSK, and PKA inhibitor.Commonly occurring plant polyphenol, inhibitor of glutathione S-transferase. Used for the assay of factor XIIa in plasma.Contact activation in blood coagulation.

Solubility
Slightly soluble in water. Soluble in 1M sodium hydroxide (10 mg/ml), EtOH, and pyridine.

Notes
Air sensitive and light sensitive. Store under dry inert gas. Store in cool dry place in tightly closed container. Store in dark and away form air.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P312 - Call a POISON CENTER or doctor if you feel unwell

    P332 + P313 - If skin irritation occurs: Get medical advice/attention

    P337 + P313 - If eye irritation persists: Get medical advice/attention