L-Glutathione, reduced, 97%
L-Glutathione, reduced, 97%
L-Glutathione, reduced, 97%
Thermo Scientific Chemicals

L-Glutathione, reduced, 97%

CAS: 70-18-8 | C10H17N3O6S | 307.321 g/mol
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Catalog number A18014.06
also known as A18014-06
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5 g
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Price (EUR)
44,65
Online Exclusive
49,00
Save 4,35 (9%)
Each
Chemical Identifiers
CAS70-18-8
IUPAC Name2-amino-4-({1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl}carbamoyl)butanoic acid
Molecular FormulaC10H17N3O6S
InChI KeyRWSXRVCMGQZWBV-UHFFFAOYNA-N
SMILESNC(CCC(=O)NC(CS)C(=O)NCC(O)=O)C(O)=O
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SpecificationsSpecification SheetSpecification Sheet
Optical Rotation-17.0 ± 1.5? (C=2 in water)
Appearance (Color)White
FormCrystals or powder or crystalline powder
Assay (Aqueous acid-base Titration)≥96.0 to ≤104.0%
Identification (FTIR)Conforms
L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Calborean, A.; Martin, F.; Marconi, D.; Turcu, R.; Kacso, I. E.; Iarinca, L. B.; Graur, F.; Turcu, I. Adsorption mechanisms of l-Glutathione on Au and controlled nano-patterning through Dip Pen Nanolithography. Mater. Sci. Eng., C 2015, 57, 171-180.
  2. Wang, X.; Chen, X.; Evans, D. G.; Yang, W. A novel biosensor for reduced l-glutathione based on cobalt phthalocyaninetetrasulfonate-intercalated layered double hydroxide modified glassy carbon electrodes. Sens. Actuators, B 2011, 160 (1), 1444-1449.