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2,4,5,6-Tetraaminopyrimidine sulfate, 97%
2,4,5,6-Tetraaminopyrimidine sulfate, 97%
2,4,5,6-Tetraaminopyrimidine sulfate, 97%
Thermo Scientific Chemicals

2,4,5,6-Tetraaminopyrimidine sulfate, 97%

CAS: 5392-28-9 | C4H10N6O4S | 238.22 g/mol
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Catalog number A18788.09
also known as A18788-09
Price (EUR)
29,10
Each
Quantity:
10 g
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Price (EUR)
29,10
Each
Chemical Identifiers
CAS5392-28-9
IUPAC Namepyrimidine-2,4,5,6-tetramine; sulfuric acid
Molecular FormulaC4H10N6O4S
InChI KeyMQEFDQWUCTUJCP-UHFFFAOYSA-N
SMILESOS(O)(=O)=O.NC1=NC(N)=C(N)C(N)=N1
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SpecificationsSpecification SheetSpecification Sheet
Assay (Aqueous acid-base Titration)≥96.0% to ≤104.0% (Dry wt. basis)
Loss on Drying≤9% (1g, 150°C, 3hrs)
Appearance (Color)Ochre to brown
FormCrystalline powder or powder
Used as an intermediate in the production of Methotrexate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Used as an intermediate in the production of Methotrexate.

Solubility
Soluble in water and dimethyl sulfoxide.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only

General References:

  1. Chiosis G; Lucas B; Shtil A; Huezo H; Rosen N. Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase. Bioorg Med Chem., 2002, 10 (11), 3555-64.
  2. Palanki, M., et al. Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction. J. Med. Chem., 2007, 50(18), 4279-4294.