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Citations & References (5)
Invitrogen™
BODIPY™ TR Cadaverine (5-(((4-(4,4-Difluoro-5-(2-Thienyl)-4-Bora-3a,4a-Diaza-s-Indacene-3-yl)phenoxy)acetyl)amino)pentylamine, Hydrochloride)
The amine-containing BODIPY™ TR cadaverine can be reversibly coupled to aldehydes and ketones to form a Schiff base - whichRead more
| Catalog Number | Quantity |
|---|---|
| D6251 also known as D-6251 | 5 mg |
Catalog number D6251
also known as D-6251
Price (EUR)
496,00
Each
Quantity:
5 mg
Price (EUR)
496,00
Each
The amine-containing BODIPY™ TR cadaverine can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC (E2247). The electronically neutral BODIPY™ TR dye is spectrally similar to the red fluorescent Texas Red™™ dye.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Chemical ReactivityCarboxylic Acid, Ketone, Aldehyde
Label or DyeBODIPY™ TR
Product TypeTR Cadaverine
Quantity5 mg
Reactive MoietyAmine, Cadaverine
Shipping ConditionRoom Temperature
Label TypeBODIPY Dyes
Product LineBODIPY
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Citations & References (5)
Citations & References
Abstract
Kinetics of penetration influence the apparent potency of vanilloids on TRPV1.
Journal:Mol Pharmacol
PubMed ID:16418338
'Evidence that the ligand binding site of TRPV1 lies on the inner face of the plasma membrane and that much of the TRPV1 itself is localized to internal membranes suggests that the rate of ligand entry into the cell may be an important determinant of the kinetics of ligand action.
Antimicrobial peptides: the LPS connection.
Journal:Methods Mol Biol
PubMed ID:20094863
'An expanding body of evidence is rendering manifest that many cationic antimicrobial peptides are endowed with different properties and activities, well beyond their direct action on microbes. One of the most interesting and potentially important research avenue on the alternative use of antimicrobial peptides grounds on their affinity toward lipopolysaccharide
Self-delivering nanoemulsions for dual fluorine-19 MRI and fluorescence detection.
Journal:J Am Chem Soc
PubMed ID:18266363
We report the design, synthesis, and biological testing of highly stable, nontoxic perfluoropolyether (PFPE) nanoemulsions for dual 19F MRI-fluorescence detection. A linear PFPE polymer was covalently conjugated to common fluorescent dyes (FITC, Alexa647 and BODIPy-TR), mixed with pluronic F68 and linear polyethyleneimine (PEI), and emulsified by microfluidization. Prepared nanoemulsions (<200
Probing the cathepsin D using a BODIPY FL-pepstatin A: applications in fluorescence polarization and microscopy.
Journal:J Biochem Biophys Methods
PubMed ID:10737220
Redistribution of cathepsin D, a major lysosomal aspartic endopeptidase, has been related to various pathological progressions during tumor formation and oxidation stress. We have synthesized a fluorescent probe for cathepsin D, where the pepstatin A was covalently conjugated with the BODIPY (Boron dipyrromethene difluoride) fluorophore. In vitro, BODIPY FL-pepstatin A
Anti-endotoxin agents. 1. Development of a fluorescent probe displacement method optimized for the rapid identification of lipopolysaccharide-binding agents.
Journal:Comb Chem High Throughput Screen
PubMed ID:15134530
Lipopolysaccharides (LPS), otherwise termed 'endotoxins', are outer-membrane constituents of Gram-negative bacteria. Lipopolysaccharides play a key role in the pathogenesis of 'Septic Shock', a major cause of mortality in the critically ill patient. Therapeutic options aimed at limiting downstream systemic inflammatory processes by targeting lipopolysaccharide do not exist at the present