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1,2,2,6,6-Pentamethylpiperidine, 97%, Thermo Scientific Chemicals
Catalog number: H27729.06
5 g, Each
Thermo Scientific Chemicals
1,2,2,6,6-Pentamethylpiperidine, 97%, Thermo Scientific Chemicals
Catalog number: H27729.06
5 g, Each
Quantity
Catalog number: H27729.06
also known as H27729-06
Price (EUR)
72,90 Online price
81,00
Each
Quantity
-
Chemical Identifiers
CAS
79-55-0
IUPAC Name
1,2,2,6,6-pentamethylpiperidin-1-ium
Molecular Formula
C10H22N
InChI Key
XULIXFLCVXWHRF-UHFFFAOYSA-O
SMILES
C[NH+]1C(C)(C)CCCC1(C)C
Specifications
Specification SheetForm
Liquid
Appearance (Color)
Clear colorless to pale yellow
Refractive Index
1.4570-1.4620 @ 20?C
Identification (FTIR)
Conforms
Assay (GC)
≥96.0%
Description
Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.
Solubility
Soluble in toluene, dimethylformamide.
Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.
Solubility
Soluble in toluene, dimethylformamide.
Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Flammable liquids
Category 3
Acute oral toxicity
Category 3
Skin Corrosion/Irritation
Category 2
Serious Eye Damage/Eye Irritation
Category 2
Specific target organ toxicity - (single exposure)
Category 3
Label Elements
Signal Word
Danger
Hazard Statements
H301 - Toxic if swallowed
H315 - Causes skin irritation
H319 - Causes serious eye irritation
H335 - May cause respiratory irritation
Physical Hazards
H226 - Flammable liquid and vapor
Precautionary Statements
P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
P280 - Wear protective gloves/protective clothing/eye protection/face protection
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
P302 + P352 - IF ON SKIN: Wash with plenty of soap and water