3-Methyl-4-nitro-1H-pyrazole, 97%

Name: 3-Methyl-4-nitro-1H-pyrazole, 97%
SKU: H30860.14
Price: 219.00 EUR

CAS: 5334-39-4 | C4H5N3O2 | 127.10 g/mol

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Catalog number H30860.14

also known as H30860-14

Price (EUR)

219,00

Each

Quantity:

25 g

Request bulk or custom format

Price (EUR)

219,00

Each

Chemical Identifiers

CAS5334-39-4

IUPAC Name5-methyl-4-nitro-1H-pyrazole

Molecular FormulaC4H5N3O2

InChI KeyWTZYTQJELOHMMJ-UHFFFAOYSA-N

SMILESCC1=C(C=NN1)[N+]([O-])=O

Specifications

Specification Sheet

Appearance (Color)White to pale cream to cream to yellow

Assay (GC)≥96.0%

Melting Point (clear melt)129.0-139.0?C

FormCrystals or powder or crystalline powder

3-Methyl-4-nitropyrazole is a reactant used in the preparation of aminopyrazole derivatives as potent, selective and brain penetrant Leucine-rich repeat kinase 2(LRRK2) small molecule inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Methyl-4-nitropyrazole is a reactant used in the preparation of aminopyrazole derivatives as potent, selective and brain penetrant Leucine-rich repeat kinase 2(LRRK2) small molecule inhibitors.

Solubility
Slightly soluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

RUO – Research Use Only

General References:

Estrada, A.A., et. al. Discovery of Highly Potent, Selective, and Brain-Penetrant Aminopyrazole Leucine-Rich Repeat Kinase 2 (LRRK2) Small Molecule Inhibitors. J. Med. Chem,2014, 57(3), 921-936.
K Chang, MR Grimmett; DD Ward; and RT Weavers. The Nitration of Brominated Pyrazoles in Aqueous Sulfuric Acid. Australian Journal of Chemistry,1979, 32 (8), 1727 - 1734.