Thermo Scientific Chemicals

N-Hydroxysulfosuccinimide sodium salt, 97%, Thermo Scientific Chemicals

Catalog number: H52795.MD
250 mg, Each
Thermo Scientific Chemicals

N-Hydroxysulfosuccinimide sodium salt, 97%, Thermo Scientific Chemicals

Catalog number: H52795.MD
250 mg, Each
Quantity
Catalog number: H52795.MD
also known as H52795-MD
Price (EUR)
Price: 117,00
Online price: 105,30
Your price:
Quantity
-

Chemical Identifiers

CAS
106627-54-7
IUPAC Name
sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate
Molecular Formula
C4H4NNaO6S
InChI Key
RPENMORRBUTCPR-UHFFFAOYNA-M
SMILES
[Na+].ON1C(=O)CC(C1=O)S([O-])(=O)=O
Assay (unspecified)
≥96.0%
Appearance (Color)
White to Pale yellow
Residual water
≤1%
Form
Powder

Description

N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Hydroxysulfosuccinimide sodium salt is used as crosslinking agents for preparing hydrophilic active esters. It is also used to activate carboxylic acids to the more reactive succinimidyl esters for coupling, biotinylation and conjugation with fluorophores. Further, it acts as a hydrophilic ligand and also used in covalently binding proteins to carboxyl containing beads, resins, other nanoparticles. It is involved in the conversion of carboxyl groups to primary amine-reactive sulfo-NHS esters.

Solubility
Soluble in methanol and water.

Notes
Store in a cool place. Moisture sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    H335 - May cause respiratory irritation

    Precautionary Statements

    P280 - Wear protective gloves and eye/face protection

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P312 - Call a POISON CENTER or doctor if you feel unwell

    P332 + P313 - If skin irritation occurs: Get medical advice/attention

    P337 + P313 - If eye irritation persists: Get medical advice/attention