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Everolimus, Thermo Scientific Chemicals
Catalog number: J60139.LB0
5 mg, Each
Thermo Scientific Chemicals
Everolimus, Thermo Scientific Chemicals
Catalog number: J60139.LB0
5 mg, Each
Quantity
Catalog number: J60139.LB0
also known as J60139-#0
Price (EUR)
135,00 Online price
150,00
Each
Quantity
-
Chemical Identifiers
CAS
159351-69-6
IUPAC Name
(1R,9S,12S,15R,16Z,18R,19R,21R,23S,24E,26Z,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0⁴,⁹]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone
Molecular Formula
C53H83NO14
InChI Key
HKVAMNSJSFKALM-CNPAPGRKSA-N
SMILES
CO[C@@H]1C[C@H](C[C@@H](C)[C@@H]2CC(=O)[C@H](C)C=C(C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=C/C=C(C)/[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1OCCO
Specifications
Specification SheetForm
Powder or crystals or crystalline powder or granules or amorphous solid
Appearance (Color)
White to off-white to pale yellow
Assay from Suppliers CofA
≥95.0%
Description
Everolimus is a rapamycin analog. It is used to treat certain types of kidney cancer, breast cancer and brain tumor. It prevents transplant rejection by decreasing the activity of the immune system. It also act as a kinase inhibitor. It is used in the treatment of subependymal giant cell astrocytoma (SEGA; a type of brain tumor) in adults and children 1 year of age and older who have TSC.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Notes
Incompatible with strong oxidizing agents.
Soluble in dimethysulfoxide,ethanol and chloroform. Slightly soluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
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Safety and Handling
Classification of the substance or mixture
CLP classification - Regulation(EC) No 1272/2008
Specific target organ toxicity - (repeated exposure)
Category 1
Label Elements
Signal Word
Danger
Hazard Statements
H372 - Causes damage to organs through prolonged or repeated exposure
Precautionary Statements
P260 - Do not breathe dust/fume/gas/mist/vapors/spray
P314 - Get medical advice/attention if you feel unwell