Thermo Scientific Chemicals

6,9-Dichloro-2-methoxyacridine, 98%, Thermo Scientific Chemicals

Catalog number: L05913.14
25 g, Each
Thermo Scientific Chemicals

6,9-Dichloro-2-methoxyacridine, 98%, Thermo Scientific Chemicals

Catalog number: L05913.14
25 g, Each
Quantity
Catalog number: L05913.14
also known as L05913-14
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
86-38-4
IUPAC Name
6,9-dichloro-2-methoxyacridine
Molecular Formula
C14H9Cl2NO
InChI Key
RYRNQWYNHLLOGX-UHFFFAOYSA-N
SMILES
COC1=CC=C2N=C3C=C(Cl)C=CC3=C(Cl)C2=C1
Assay (Non-aqueous acid-base Titration)
≥97.5 to ≤102.5%
Assay (HPLC)
≥97.5%
Melting Point (clear melt)
160.0-166.0?C
Appearance (Color)
Yellow to yellow-green
Form
Powder

Description

6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N'-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N'-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
6,9-Dichloro-2-methoxyacridine is used to prepare 6-chloro-2-methoxy-acridin-9-ylamine by reacting with phenol and ammonium carbonate. It is used in the preparation of 9-amino-6-chloro-2-methoxyacridine, N′-(6-Chloro-2-methoxy-acridin-9-yl)-heptylamine and N,N′-bis-(6-chloro-2-methoxy-acridin-9-yl)-hexane-1,6-diamine. Further, it is involved in the preparation of 4-aminoquinoline and 9-aminoacridine derivatives by reaction with quinolizidinylalkylamines.

Solubility
Insoluble in water.

Notes
Incompatible with oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Respiratory Sensitization
    Category 1
    Skin Sensitization
    Category 1
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H315 - Causes skin irritation

    H317 - May cause an allergic skin reaction

    H319 - Causes serious eye irritation

    H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled

    H335 - May cause respiratory irritation

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P312 - Call a POISON CENTER or doctor if you feel unwell

    P333 + P313 - If skin irritation or rash occurs: Get medical advice/attention

    P337 + P313 - If eye irritation persists: Get medical advice/attention