Thermo Scientific Chemicals

Diethyl (bromodifluoromethyl)phosphonate, 97%, Thermo Scientific Chemicals

Catalog number: L16715.06
5 g, Each
Thermo Scientific Chemicals

Diethyl (bromodifluoromethyl)phosphonate, 97%, Thermo Scientific Chemicals

Catalog number: L16715.06
5 g, Each
Quantity
Catalog number: L16715.06
also known as L16715-06
Price (EUR)
Price: 97,00
Online price: 87,30
Your price:
Quantity
-

Chemical Identifiers

CAS
65094-22-6
IUPAC Name
diethyl (bromodifluoromethyl)phosphonate
Molecular Formula
C5H10BrF2O3P
InChI Key
QRADKVYIJIAENZ-UHFFFAOYSA-N
SMILES
CCOP(=O)(OCC)C(F)(F)Br
Appearance (Color)
Clear colorless
Form
Liquid
Refractive Index
1.4150-1.4190 @ 20?C
Assay (GC)
>96.0%

Description

Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethyl (bromodifluoromethyl)phosphonate is used as a reactant for the preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3), synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps and P-C bond cleavage on basic hydrolysis.

Solubility
Not miscible or difficult to mix in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Incompatible with oxidizing agents.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 2
    Label Elements
    Signal Word

    Warning

    Hazard Statements

    H315 - Causes skin irritation

    H319 - Causes serious eye irritation

    Precautionary Statements

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P332 + P313 - If skin irritation occurs: Get medical advice/attention

    P337 + P313 - If eye irritation persists: Get medical advice/attention