CTS™ DynaMag™ Magnet
Gibco™

CTS™ DynaMag™ Magnet

The CTS™ DynaMag™ Magnet is suitable for use with commercially available sterile blood/culture bags, tubing, and connectors.Benefits:• Ideal for magneticAfficher plus
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RéférenceQuantité
121021 de chaque
Référence 12102
Prix (EUR)
28 940,00
Each
Quantité:
1 de chaque
Prix (EUR)
28 940,00
Each
The CTS™ DynaMag™ Magnet is suitable for use with commercially available sterile blood/culture bags, tubing, and connectors.

Benefits:
• Ideal for magnetic isolation in closed, sterile blood bags
• Scalable volumes: 50 to 330 mL in static separations and >10 L in continuous flow separations following T-cell expansion protocols
• Residual beads that escape initial magnetic capture are retained on a secondary magnet

Applications:
• Positive isolation of CD3+ T-cells for subsequent stimulation/expansion with CTS™ Dynabeads™ CD3/CD28 and removal of CTS Dynabeads CD3/CD28 following T-cell expansion

The CTS DynaMag Magnet is intended for use with the CTS Dynabeads product portfolio in clinical research such as CTS Dynabeads CD3/CD28 (Cat. No. 40203D).

À des fins de recherche ou de fabrication de produits à base de cellules, de gènes ou de tissus. MISE EN GARDE : Non destiné à être directement administré à des humains ou des animaux.

Spécifications
À utiliser avec (équipement)DynaMag™
Gamme de produitsCTS, DynaMag
Quantité1 de chaque
Catégorie de rechercheCell Therapy Research
Conditions d’expéditionRoom Temperature
Unit SizeEach
Contenu et stockage
The product contains: CTS DynaMag Magnet

Storage Conditions:
Protect the device from vibration and keep out of direct sunlight.

Foire aux questions (FAQ)

What are the Gauss levels for the DynaMag-2 and DynaMag-Spin Magnets?

The DynaMag-2 Magnet is 3,500-3,700 minimum Gauss level and the DynaMag-Spin is 3,000-3,500 minimum Gauss level.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

What is the standard conversion of Gauss to Tesla units?

1 Tesla is equivalent to 10,000 Gauss. .

How can I clean my DynaMag magnet?

Spray and/or wipe the DynaMag magnet unit with one of the following cleaning agents:

- 70% (v/v) isopropyl alcohol
- 1% (v/v) sodium hypochlorite solution (bleach)
- 0.1 N HCl solution

Do not submerge the magnet unit in aqueous solutions and avoid prolonged exposure to water or aqueous solutions. Clean with a damp cloth and mild detergent when exposed to harsh solvents. Do not autoclave the magnet unit as heating the magnet to above 70 degrees C can destabilize the magnetic material, resulting in loss of magnetic strength.

What is the difference between the DynaMag-2 Magnet (Cat. No. 12321D) and DynaMag-Spin Magnet (Cat. No. 12320D)?

The DynaMag-2 Magnet can hold 16 standard 1.5 mL or 2 mL microcentrifuge tubes, while the DynaMag-Spin Magnet holds up to 6 standard 1.5 mL microcentrifuge tubes.

How can I clean my DynaMag magnet?

Spray and/or wipe the DynaMag magnet unit with one of the following cleaning agents:

- 70% (v/v) isopropyl alcohol
- 1% (v/v) sodium hypochlorite solution (bleach)
- 0.1 N HCl solution

Do not submerge the magnet unit in aqueous solutions and avoid prolonged exposure to water or aqueous solutions. Clean with a damp cloth and mild detergent when exposed to harsh solvents. Do not autoclave the magnet unit as heating the magnet to above 70 degrees C can destabilize the magnetic material, resulting in loss of magnetic strength.

Find additional tips, troubleshooting help, and resources within our Protein Assays and Analysis Support Center.

Citations et références (2)

Citations et références
Abstract
Manufacturing validation of biologically functional T cells targeted to CD19 antigen for autologous adoptive cell therapy.
Authors:Hollyman D, Stefanski J, Przybylowski M, Bartido S, Borquez-Ojeda O, Taylor C, Yeh R, Capacio V, Olszewska M, Hosey J, Sadelain M, Brentjens RJ, Rivière I,
Journal:J Immunother
PubMed ID:19238016
On the basis of promising preclinical data demonstrating the eradication of systemic B-cell malignancies by CD19-targeted T lymphocytes in vivo in severe combined immunodeficient-beige mouse models, we are launching phase I clinical trials in patients with chronic lymphocytic leukemia (CLL) and acute lymphoblastic leukemia. We present here the validation of ... More
Simplified process for the production of anti-CD19-CAR-engineered T cells.
Authors:Tumaini B, Lee DW, Lin T, Castiello L, Stroncek DF, Mackall C, Wayne A, Sabatino M,
Journal:
PubMed ID:23992830
Adoptive immunotherapy with the use of chimeric antigen receptor (CAR)-engineered T cells specific for CD19 has shown promising results for the treatment of B-cell lymphomas and leukemia. This therapy involves the transduction of autologous T cells with a viral vector and the subsequent cell expansion. We describe a new, simplified ... More