Axiom™ Genome-Wide Human Origins 1 Array Plate
Axiom™ Genome-Wide Human Origins 1 Array Plate
Applied Biosystems™

Axiom™ Genome-Wide Human Origins 1 Array Plate

Axiom Genome-Wide Human Origins 1 Array is a unique genotyping panel optimized for population geneticists that has been designed inRead more
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Catalog NumberQuantity
9018531 plate
Catalog number 901853
Price (HKD)
-
Quantity:
1 plate
Axiom Genome-Wide Human Origins 1 Array is a unique genotyping panel optimized for population geneticists that has been designed in collaboration with leading investigators, solely for studying human history, migration, and natural selection. The Array has genomic markers from 11 different modern human populations and archaic hominids. Each marker has been cleanly ascertained in samples of known ancestry, is well annotated and genotype-tested, enabling robust statistical analysis and avoiding the confounding biases that can be introduced by use of GWAS arrays for population genetic studies.

Benefits of Axiom Genome-Wide Human Origins 1 Array:
• Establishes a common set of ~629,000 SNPs that can be typed in diverse populations
• Includes markers from 11 modern human populations, making it a valuable tool for population geneticists and evolutionary biologists as well as for consumer genomic firms that offer ancestry testing
• SNPs were selected from sites with read coverage from Neanderthals, Denisovans, and chimpanzees, enabling the users to compare data from modern humans to archaic hominids and apes
• Includes SNPs that were cleanly ascertained and well-documented, overcoming the limitations and drawbacks of SNP arrays otherwise designed for use in medical genetics and GWAS studies
• Each marker is high-quality and genotype-tested for high sample pass rate, call rate, and reproducibility
• Supports diverse sample inputs including blood, saliva, cell line, and whole-genome amplified DNA
• Compatible with the Axiom 2.0 Reagent Kit, GeneTitan MC Instrument's automated or manual workflow, and Axiom Analysis Suite

Reference genotyped data was generated against 943 unrelated individuals from the Human HGDP-CEPH (Human Genome Diversity Cell Line Panel). This genotype dataset (Harvard HGDP-CEPH Genotypes) is available as Dataset 11 at http://www.cephb.fr/en/hgdp_panel.php

Required Products
Axiom Analysis Suite
GeneChip Command Console Software
GeneTitan Multi-Channel Instrument
For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Application)Microarray Analysis
Quantity1 plate
ArrayGenotyping
Format96-array Plate
Number of Arrays96 arrays
SpeciesHuman
Unit SizeEach

Frequently asked questions (FAQs)

Is the hybridization mix for cartridges the same as the hybridization mix for PEG arrays (array plates)?

The hybridization mix for PEG arrays is different from the hybridization mix for cartridges. The concentrations of the hybridization mix are different and in addition, DMSO is not added into the hybridization mix for PEG arrays because it can affect the glue that holds the PEG to the plate.

What is the starting amount of DNA required for Axiom arrays?

All Axiom arrays (except for Axiom Genome-Wide Pan-African Array Set) require a total of 200 ng DNA. The Axiom Genome-Wide Pan-African Array Set requires a total of 300 ng DNA, or 100 ng DNA per array (there are 3 arrays).

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.

What are the sample requirements for Axiom array processing at the Thermo Fisher Scientific Microarray Research Services Laboratory (MRSL)?

For information regarding our in-house MRSL requirements, please contact us via phone at 888-362-2447 (in North America) or via email at BioinformaticsServices@thermofisher.com.

Find additional tips, troubleshooting help, and resources within our Microarray Analysis Support Center.