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引用資料與參考文獻 (64)
Invitrogen™
NBD Cholesterol (22-(N-(7-Nitrobenz-2-Oxa-1,3-Diazol-4-yl)Amino)-23,24-Bisnor-5-Cholen-3β-Ol)
This fluorescent analog, NBD cholesterol, is an environment-sensitive probe that localizes in the membrane's interior and is useful for investigating深入閱讀
| 產品號碼 | Quantity |
|---|---|
| N1148 | 10 mg |
產品號碼 N1148
價格 (HKD)
4,198.00
Each
Quantity:
10 mg
價格 (HKD)
4,198.00
Each
This fluorescent analog, NBD cholesterol, is an environment-sensitive probe that localizes in the membrane's interior and is useful for investigating lipid transport processes as well lipid-protein interactions.
We recommend dissolving in chloroform (CHCl3) or acetonitrile (MeCN) to attain a stock concentration up to 1 mM.
For Research Use Only. Not for use in diagnostic procedures.
規格
Chemical Name or MaterialCholesterol Analogs
Excitation/Emission469/537 nm
Recommended StorageStore at room temperature and protect from light.
Physical FormSolid
Product LineInvitrogen
Quantity10 mg
Unit SizeEach
引用資料與參考文獻 (64)
引用資料與參考文獻
Abstract
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.
Journal:J Biol Chem
PubMed ID:15671032
'NPC1L1, a recently identified relative of Niemann-Pick C1, was characterized to determine its subcellular location and potential function(s). NPC1L1 was highly expressed in HepG2 cells and localized in a subcellular vesicular compartment rich in the small GTPase Rab5. mRNA expression profiling revealed significant differences between mouse and man with highest
High density lipoprotein-mediated cholesterol uptake and targeting to lipid droplets in intact L-cell fibroblasts. A single- and multiphoton fluorescence approach.
Journal:J Biol Chem
PubMed ID:10777574
'Fluorescent sterols, dehydroergosterol and NBD-cholesterol, were used to examine high density lipoprotein-mediated cholesterol uptake and intracellular targeting in L-cell fibroblasts. The uptake, but not esterification or targeting to lipid droplets, of these sterols differed >100-fold, suggesting significant differences in uptake pathways. NBD-cholesterol uptake kinetics and lipoprotein specificity reflected high density
Lipid binding to sterol carrier protein-2 is inhibited by ethanol.
Journal:Biochim Biophys Acta
PubMed ID:9931423
'Sterol carrier protein-2 (SCP-2) is an intracellular lipid carrier protein that binds cholesterol, phospholipids, fatty acids and other ligands. It has been reported that expression of SCP-2 was increased in brain nerve endings or synaptosomes of chronic ethanol-treated mice and it was shown that cholesterol homeostasis was altered in brain
Formation of membrane domains created during the budding of vesicular stomatitis virus. A model for selective lipid and protein sorting in biological membranes.
Journal:Biochemistry
PubMed ID:7543280
'Vesicular stomatitis virus buds from domains of the plasma membrane that have a unique protein and lipid composition. Fluorescence digital imaging microscopy and resonance energy transfer were used to determine how the two viral envelope-associated proteins, the G and the M proteins, could alter the lateral distribution of lipids in
Membrane properties of D-erythro-N-acyl sphingomyelins and their corresponding dihydro species.
Journal:Biophys J
PubMed ID:11325733
'We have prepared acyl chain-defined D-erythro-sphingomyelins and D-erythro-dihydrosphingomyelins and compared their properties in monolayer and bilayer membranes. Surface pressure/molecular area isotherms of D-erythro-N-16:0-sphingomyelin (16:0-SM) and D-erythro-N-16:0-dihydrosphingomyelin (16:0-DHSM) show very similar packing properties, except that the expanded-to-condensed phase transition (crystallization) occurs at a lower surface pressure for 16:0-DHSM. The measured surface